Human OGG1 

Cat# BB-PE0245 100µg (1mg/ml)

Product type: Human OGG1 Protein.

Source: Recombinant His Tag protein expressed in E. coli

Alternative Name: HMMH, HOGG1, MUTM, OGH1

Purity: >95%, by SDS-PAGE under reducing conditions and visualized by coomassie stain.

Protein Sequence:

HHHHHHSSGLVPRGSHTGSMPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSG
QSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQL
DVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQ
AFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQ
QLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQ
AKGPSPQTNK ELGNFFRSLWGPYAGWAQAVLFSADLRQCRHAQEPPAKRRKGSKGPEG

Formulation: Supplied as a 0.2 μm filtered solution in PBS at 100 μg (1mg/ml) containing 50% Glycerol.

Stability: Stable for 1 year at -20°C

Description: OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7, 8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS). OGG1 shows beta lyase activity that nicks DNA 3” to the lesion.

Storage instructions: Store at -20°C (Recommended).